According to the companies, the new technology--called scientific CMOS (sCMOS)--will benefit many microscopy applications such as live-cell, super-resolution, and spinning-disk confocal microscopy as well as TIRF, FRAP, FRET, and single molecule detection.
The technology looks to be a significant advancement for biological imaging because it overcomes some of the drawbacks of many sensor technologies, including interline CCDs and electron multiplying (EM) CCDs, which are often used in demanding microscopy applications. sCMOS can simultaneously provide low noise, rapid frame rates, wide dynamic range, high quantum efficiency (QE), high resolution, and a large field of view.
Here are the numbers for the first sCMOS sensor:
- Sensor format: 5.5 megapixels (2560(h) x 2160(v))
- Read noise: <> 16,000:1 (@ 30 frames/s)
- QEmax.: 60%
- Read out modes: Rolling and Global shutter (user selectable)
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The technology looks to be a significant advancement for biological imaging because it overcomes some of the drawbacks of many sensor technologies.Technology News